The tobacco industry has a substantial history of using racial profiling, demographics of an area, and cultural factors to target particular communities and promote tobacco use. Nicotine creates a temporary feeling of well-being and relaxation, and increases heart rate and the amount of oxygen the heart uses. As nicotine enters the body, it causes a surge of endorphins, which are chemicals that help to relieve stress and pain and improve mood. Native people of these areas originally used the leaves of tobacco plants to chew, smoke, or use in religious rituals. European colonists exported tobacco crops for profit and changed the focus of tobacco to recreational use.

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Bupropion is a medicine originally used to treat depression, but it has since been found to help people quit smoking. It's taken as tablets. A photoactivatable form of nicotine, which releases nicotine when exposed to ultraviolet light with certain conditions, has been developed for studying nicotinic acetylcholine receptors in brain tissue. [200] Oral health [ edit ]

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NRT may include nicotine patches, sprays, lozenges, or gum. FDA-approved NRTs are the least harmful types of nicotine products. Medications It is also a toxic substance that can cause poisoning. If people suspect they have nicotine poisoning, they will require immediate medical help. The amount of nicotine absorbed by the body from smoking can depend on many factors, including the types of tobacco, whether the smoke is inhaled, and whether a filter is used. However, it has been found that the nicotine yield of individual products has only a small effect (4.4%) on the blood concentration of nicotine, [145] suggesting "the assumed health advantage of switching to lower-tar and lower-nicotine cigarettes may be largely offset by the tendency of smokers to compensate by increasing inhalation". Possible alteration of nicotine absorption through the nasal cavity from the nicotine nasal spray by nasal vasoconstrictors (e.g., xylometazoline). [75] Kohlmeier KA (June 2015). "Nicotine during pregnancy: changes induced in neurotransmission, which could heighten proclivity to addict and induce maladaptive control of attention". Journal of Developmental Origins of Health and Disease. 6 (3): 169–81. doi: 10.1017/S2040174414000531. PMID 25385318. S2CID 29298949.

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Medications, nicotine replacement therapies, and behavioral treatment can help people to stop using products that contain nicotine.

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Nicotine Transdermal Patch" (PDF). United States Food and Drug Administration . Retrieved 24 January 2019.